Unless your bike has lots of range, you had better gas up in Lakeview, because unless the little two-nozzle gas pump 84 miles north in Wagontire is available (it wasn't when I went through), you have over 110 miles to Riley, where 395 briefly joins U.S. 20. Although you initially follow the banks of some large, shallow (and sometimes stinky) lakes, the terrain here is sort of high desert, cresting a couple of passes in the 5000-foot range. The land is open and, though not barren, treeless and deserted...like the road. I had been riding with no other cars in sight and realized that I hadn't seen a southbound car for some time. It was 16 miles before a car came along. If you want to leave the world behind, 395 in Oregon is a great place to do it. However, with such a well maintained, non-challenging highway with no traffic, the 55-mph speed limit seems an unnecessary annoyance.